A force balanced generalized molecular fractionation with conjugate caps (FB-GMFCC) method is proposed for ab initio molecular dynamic simulation of proteins.In this approach, the energy of the protein is computed by a linear combination of the QM energies of individual residues and molecular fragments that account for the two-body interaction of h

Controlling stimulus access to sensory organs allows animals to optimize sensory reception and prevent damage.The vomeronasal organ (VNO) detects pheromones and other semiochemicals to regulate innate social and sexual behaviors.This semiochemical detection generally requires the VNO to draw in chemical fluids, such as bodily secretions, which are

Extreme typhoon rainfall can lead to damaging floods near the coastal region in mainland China.In the present study, we calibrate the parameters for a parametric hurricane rain model by using the precipitation radar (PR) data from the Tropical Rainfall Measuring Mission (TRMM) (i.e., PR-TRMM) and the TRMM microwave imager (TMI) data (i.e., TMI-TRMM

This article has the purpose to present Pennsylvania some reflexions about the place of ludicity in learning and in the development of the child, in the case of the six year old, that, according to the new legislation, are in the first year of elementary school.To allow the experience of ludic activities in educational practices in this level of te

Although the fibrinogen-to-albumin ratio (F/R ratio) has been used as an inflammation marker to predict clinical outcomes in patients with cardiovascular diseases, its association with the prognosis of patients with coronavirus disease 2019 (COVID-19) remains unclear.Electronic databases including EMBASE, MEDLINE, Google Scholar, and Cochrane Libra